Each year, the AIPAC National Summit attracts a wide range of notable speakers, including elected officials, scholars and activists from both the United States and Israel.

The following speakers are among those who joined AIPAC leaders at this year's National Summit:

• The Honorable Ehud Barak, Minister of Defense, Israel
• The Honorable Arlen Specter, R-PA
• The Honorable Robert P. Casey, Jr., D-PA
• The Honorable Robert Menendez, D-NJ
• The Honorable Frank Lautenberg, D-NJ
• Ambassador Zalmay Khalilzad, U.S. Permanent Representative to the United Nations
• Ambassador Marc Ginsberg, Former U.S. Ambassador to Morocco
• Professor Elie Wiesel, Nobel Peace Prize Winner and Boston University Professor
• Natan Sharansky, Chairman, Adelson Institute for Strategic Studies, Shalem Center
• Avi Dichter, Minister of Public Security, Israel
• Ken Mehlman, former Chairman, Republican National Committee
• Paul Begala, Political Analyst and CNN Commentator
• Donna Brazile, Political Commentator and Chair of the Voting Rights Institute
• William Kristol, Editor, The Weekly Standard and Panelist, FOX News Sunday
• David Horovitz, Editor in Chief, The Jerusalem Post
• David Makovsky, Director, Project on the Middle East Peace Process, Washington Institute for Near East Policy
• The Honorable Ted Deutch, D-FL, State Senator
• Dr. Daniel Pipes, Director, Middle East Forum
• Dr. Matthew Levitt, Director, Stein Program on Terrorism, Intelligence, and Policy, The Washington Institute for Near East Policy
• Ms. Lorna Fitzsimons, Chief Executive, Britain Israel Communications and Research Centre (BICOM)
• Mr. Tony Badran, Research Fellow, Levant, The Foundation for the Defense of Democracies
• Dr. Martin Kramer, Adelson Institute Senior Fellow at the Shalem Center in Jerusalem
• Mr. David Schenker, Senior Fellow in Arab Politics, The Washington Institute for Near East Policy
• Dr. Josef Joffe, Editor in Chief, Die Zeit
• Asher Susser, Professor, Brandeis University
• Meyrav Wurmser, Director, Center for Middle East Policy, Hudson Institute
• David Brog, Author, "Standing With Israel"
• Earl Cox, Founder, Israel Always
• Bill Sutter, Executive Director, Friends of Israel Gospel Ministry
• Mark Dubowitz, Chief Operating Officer and Director of The Coalition Against Terrorist Media,The Foundation for the Defense of Democracies